Inhibition of Influenza Virus Replication by DNA Aptamers Targeting a Cellular Component of Translation Initiation

Inhibition of Influenza Virus Replication by DNA Aptamers Targeting a Cellular Component of Translation Initiation

The genetic diversity of the influenza virus hinders the use of broad spectrum antiviral drugs and favors the appearance of resistant strains. Single-stranded DNA aptamers represent an innovative approach with potential application as antiviral compounds. The mRNAs of influenza virus possess a 5′cap...

Full description

Bibliographic Details
Main Authors: Paloma Rodriguez, M Isabel Pérez-Morgado, Víctor M Gonzalez, M Elena Martín, Amelia Nieto
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
aptamers
influenza virus replication
polyA-binding protein
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117300343

Similar Items

Similar Items