Endothelial Progenitor Cell Dysfunction in Myelodysplastic Syndromes: Possible Contribution of a Defective Vascular Niche to Myelodysplasia

Endothelial Progenitor Cell Dysfunction in Myelodysplastic Syndromes: Possible Contribution of a Defective Vascular Niche to Myelodysplasia

We set a model to replicate the vascular bone marrow niche by using endothelial colony forming cells (ECFCs), and we used it to explore the vascular niche function in patients with low-risk myelodysplastic syndromes (MDS). Overall, we investigated 56 patients and we observed higher levels of ECFCs i...

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Bibliographic Details
Main Authors: Luciana Teofili, Maurizio Martini, Eugenia Rosa Nuzzolo, Sara Capodimonti, Maria Grazia Iachininoto, Alessandra Cocomazzi, Emiliano Fabiani, Maria Teresa Voso, Luigi M. Larocca
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558615000457

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http://www.sciencedirect.com/science/article/pii/S1476558615000457

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