Local cryotherapy improves adjuvant-induced arthritis through down-regulation of IL-6 / IL-17 pathway but independently of TNFα.

Local cryotherapy improves adjuvant-induced arthritis through down-regulation of IL-6 / IL-17 pathway but independently of TNFα.

<h4>Objectives</h4>Local cryotherapy is widely and empirically used in the adjuvant setting in rheumatoid arthritis treatment, however its own therapeutic and anti-inflammatory effects are poorly characterized. We aimed to evaluate the effects of local cryotherapy on local and systemic i...

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Bibliographic Details
Main Authors: Xavier Guillot, Hélène Martin, Stéphanie Seguin-Py, Katy Maguin-Gaté, Johnny Moretto, Perle Totoson, Daniel Wendling, Céline Demougeot, Nicolas Tordi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0178668

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