4-Nitro-N-phthalyl-l-tryptophan

4-Nitro-N-phthalyl-l-tryptophan

The crystal structure of the title compound [systematic name: (2R)-3-(1H-indol-3-yl)-2-(4-nitro-1,3-dioxoisoindolin-2-yl)propanoic acid], C19H13N3O6, an analogue of epigenetic modulator RG108, is constrained by strong hydrogen bonds between the indole N—H group and a carbonyl O atom of...

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Main Authors: Anaelle Tilborg, Irving Boittiaux, Bernadette Norberg, Didier Lambert, Johan Wouters
Format: Article
Language:English
Published: International Union of Crystallography 2011-08-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536811029138
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spelling doaj-5492932f4c9848ed88582da5be3245992020-11-24T20:48:17ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682011-08-01678o2116o211610.1107/S16005368110291384-Nitro-N-phthalyl-l-tryptophanAnaelle TilborgIrving BoittiauxBernadette NorbergDidier LambertJohan WoutersThe crystal structure of the title compound [systematic name: (2R)-3-(1H-indol-3-yl)-2-(4-nitro-1,3-dioxoisoindolin-2-yl)propanoic acid], C19H13N3O6, an analogue of epigenetic modulator RG108, is constrained by strong hydrogen bonds between the indole N—H group and a carbonyl O atom of the phthalimide ring of a symmetry-related molecule, and between the protonated O atom of the carboxyl group and a carbonyl O atom of the phthalimide ring. π–π stacking interactions with centroid–centroid distances of 3.638 (1) and 3.610 (1) Å are also observed between indole and phthalimide rings.http://scripts.iucr.org/cgi-bin/paper?S1600536811029138
collection DOAJ
language English
format Article
sources DOAJ
author Anaelle Tilborg
Irving Boittiaux
Bernadette Norberg
Didier Lambert
Johan Wouters
spellingShingle Anaelle Tilborg
Irving Boittiaux
Bernadette Norberg
Didier Lambert
Johan Wouters
4-Nitro-N-phthalyl-l-tryptophan
Acta Crystallographica Section E
author_facet Anaelle Tilborg
Irving Boittiaux
Bernadette Norberg
Didier Lambert
Johan Wouters
author_sort Anaelle Tilborg
title 4-Nitro-N-phthalyl-l-tryptophan
title_short 4-Nitro-N-phthalyl-l-tryptophan
title_full 4-Nitro-N-phthalyl-l-tryptophan
title_fullStr 4-Nitro-N-phthalyl-l-tryptophan
title_full_unstemmed 4-Nitro-N-phthalyl-l-tryptophan
title_sort 4-nitro-n-phthalyl-l-tryptophan
publisher International Union of Crystallography
series Acta Crystallographica Section E
issn 1600-5368
publishDate 2011-08-01
description The crystal structure of the title compound [systematic name: (2R)-3-(1H-indol-3-yl)-2-(4-nitro-1,3-dioxoisoindolin-2-yl)propanoic acid], C19H13N3O6, an analogue of epigenetic modulator RG108, is constrained by strong hydrogen bonds between the indole N—H group and a carbonyl O atom of the phthalimide ring of a symmetry-related molecule, and between the protonated O atom of the carboxyl group and a carbonyl O atom of the phthalimide ring. π–π stacking interactions with centroid–centroid distances of 3.638 (1) and 3.610 (1) Å are also observed between indole and phthalimide rings.
url http://scripts.iucr.org/cgi-bin/paper?S1600536811029138
work_keys_str_mv AT anaelletilborg 4nitronphthalylltryptophan
AT irvingboittiaux 4nitronphthalylltryptophan
AT bernadettenorberg 4nitronphthalylltryptophan
AT didierlambert 4nitronphthalylltryptophan
AT johanwouters 4nitronphthalylltryptophan
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