Transcriptional Regulation in Non-Alcoholic Fatty Liver Disease

Transcriptional Regulation in Non-Alcoholic Fatty Liver Disease

Obesity is the primary risk factor for the pathogenesis of non-alcoholic fatty liver disease (NAFLD), the worldwide prevalence of which continues to increase dramatically. The liver plays a pivotal role in the maintenance of whole-body lipid and glucose homeostasis. This is mainly mediated by the tr...

Full description

Bibliographic Details
Main Authors:	Sandra Steensels, Jixuan Qiao, Baran A. Ersoy
Format:	Article
Language:	English
Published:	MDPI AG 2020-07-01
Series:	Metabolites
Subjects:	non-alcoholic fatty liver disease non-alcoholic steatohepatitis transcription factors inflammation metabolic stress fibrosis
Online Access:	https://www.mdpi.com/2218-1989/10/7/283

Similar Items

Association between sonographic diagnosis of fatty liver with histopathologic abnormalities and liver biopsy findings in middle age patient with non-alcoholic fatty liver disease
by: Hamid Kalantari, et al.
Published: (2016-01-01)

Alcohol? Not for Non-alcoholic Fatty Liver Disease Patients
by: Francesca Cainelli, et al.
Published: (2020-02-01)

Nuclear receptors and transcriptional regulation in non-alcoholic fatty liver disease
by: Yang Xiao, et al.
Published: (2021-08-01)

Improvement of Diagnostic Algorithm in Patients With Alcoholic Fatty Liver Disease by Using Non-invasive Methods of Verification of Liver Steatosis and Fibrosis
by: Svintsitskyy A., et al.
Published: (2016-07-01)

The diagnostic conundrum in non-alcoholic fatty liver disease
by: Valerio Rosato, et al.
Published: (2020-10-01)

Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome after Liver Transplant
by: Stefano Gitto, et al.
Published: (2016-04-01)

Systematic Review with Meta-Analyses: Diagnostic Accuracy of FibroMeter Tests in Patients with Non-Alcoholic Fatty Liver Disease
by: Anne-Marieke Van Dijk, et al.
Published: (2021-06-01)

A Mineralocorticoid Receptor Deficiency in Myeloid Cells Reduces Liver Steatosis by Impairing Activation of CD8+ T Cells in a Nonalcoholic Steatohepatitis Mouse Model
by: Natalia Muñoz-Durango, et al.
Published: (2020-12-01)

The Natural Course of Non-Alcoholic Fatty Liver Disease
by: Luis Calzadilla Bertot, et al.
Published: (2016-05-01)

Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis
by: Maryam Mahjoubin-Tehran, et al.
Published: (2021-08-01)

Non-alcoholic fatty liver disease and type 2 diabetes mellitus: issues of the liver fibrosis diagnostics
by: A. V. Anisonyan, et al.
Published: (2020-09-01)

Editor’s Pick: Non-Alcoholic Fatty Liver Disease – Changing the Prevalence of Liver Cancer?
by: Benedetta Campana, et al.
Published: (2015-01-01)

Should you advocate for hepatocellular carcinoma surveillance in patients with alcohol-related liver disease or non-alcoholic fatty liver disease?
by: Ju Hyun Shim
Published: (2020-04-01)

Correlation between Serum Ferritin Level and Histopathological Disease Severity in Non-alcoholic Fatty Liver Disease
by: Seyed Reza Modares Mousavi, et al.
Published: (2018-04-01)

Non-alcoholic steatohepatitis-related liver cirrhosis is increasing in China: A ten-year retrospective study
by: Ji Xiong, et al.
Published: (2015-08-01)

Epidemiology of non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis in Japan: A focused literature review
by: Yuichiro Eguchi, et al.
Published: (2020-10-01)

Liver Cirrhosis as the Outcome of Non-Alcoholic Fatty Liver Disease Associated with PNPLA3 Gene RS738409 Polymorphism
by: I. G. Nikitin, et al.
Published: (2020-03-01)

Primary care practitioners survey of non-alcoholic fatty liver disease
by: Adnan Said, et al.
Published: (2013-09-01)

Role of Extracellular Vesicles in the Pathophysiology, Diagnosis and Tracking of Non-Alcoholic Fatty Liver Disease
by: Lauren A. Newman, et al.
Published: (2020-06-01)

Serum laminin, type IV collagen and hyaluronan as fibrosis markers in non-alcoholic fatty liver disease
by: V.N. dos Santos, et al.
Published: (2005-05-01)

Obstructive Sleep Apnea and Non-alcoholic Fatty Liver Disease: Is the Liver Another Target?
by: Aibek eMirrakhimov, et al.
Published: (2012-10-01)

Reduced Lysosomal Acid Lipase Activity in Adult Patients With Non-alcoholic Fatty Liver Disease
by: Francesco Baratta, et al.
Published: (2015-07-01)

The Connection between MicroRNAs from Visceral Adipose Tissue and Non-Alcoholic Fatty Liver Disease
by: Veronika Zubáňová, et al.
Published: (2021-04-01)

Morphological basis for the assessment of steatosis, steatohepatitis and fibrosis in patients with non-alcoholic fatty liver disease associated with obesity and pathology of the biliary tract
by: Yu.M. Stepanov, et al.
Published: (2017-09-01)

Non-alcoholic fatty liver disease associated with hepatocellular carcinoma: An increasing concern
by: Ekta Dhamija, et al.
Published: (2019-01-01)

PNPLA3 Expression Is Related to Liver Steatosis in Morbidly Obese Women with Non-Alcoholic Fatty Liver Disease
by: Gemma Aragonès, et al.
Published: (2016-04-01)

Altered Fatty Acid Metabolism-Related Gene Expression in Liver from Morbidly Obese Women with Non-Alcoholic Fatty Liver Disease
by: Teresa Auguet, et al.
Published: (2014-12-01)

Pediatric non-alcoholic fatty liver disease
by: Delvin Edgard, et al.
Published: (2015-01-01)

Inflammation is not the cause of an elevated serum ferritin in non-alcoholic fatty liver disease
by: Melanie D. Beaton, et al.
Published: (2014-05-01)

Insulin resistance and metabolic syndrome are related to non-alcoholic fatty liver disease, but not visceral adiposity index, in severely obese patients
by: Rubén Díez-Rodríguez, et al.
Published: (2014-12-01)

Association between Visceral Adipose Tissue and Non-Alcoholic Steatohepatitis Histology in Patients with Known or Suspected Non-Alcoholic Fatty Liver Disease
by: Ilkay S. Idilman, et al.
Published: (2021-06-01)

Evaluating causality of cellular senescence in non-alcoholic fatty liver diseaseKey points
by: Abraham Stijn Meijnikman, et al.
Published: (2021-08-01)

Epigenetic Mechanisms Underlying the Link between Non-Alcoholic Fatty Liver Diseases and Nutrition
by: Joo Ho Lee, et al.
Published: (2014-08-01)

Non-Alcoholic Fatty Liver Disease: Metabolic, Genetic, Epigenetic and Environmental Risk Factors
by: Oriol Juanola, et al.
Published: (2021-05-01)

Gut Dysbiosis and Increased Intestinal Permeability Drive microRNAs, NLRP-3 Inflammasome and Liver Fibrosis in a Nutritional Model of Non-Alcoholic Steatohepatitis in Adult Male Sprague Dawley Rats
by: Longo L, et al.
Published: (2020-09-01)

Gut Dysbiosis and Increased Intestinal Permeability Drive microRNAs, NLRP-3 Inflammasome and Liver Fibrosis in a Nutritional Model of Non-Alcoholic Steatohepatitis in Adult Male Sprague Dawley Rats [Erratum]
by: Longo L, et al.
Published: (2020-10-01)

The Progression of Liver Fibrosis in Non-alcoholic Fatty Liver Disease
by: Moon Young Kim
Published: (2017-06-01)

Nicotinic alpha‐7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of non‐alcoholic steatohepatitis
by: Kumi Kimura, et al.
Published: (2019-05-01)

Historical narrative from fatty liver in the nineteenth century to contemporary NAFLD – Reconciling the present with the pastKey points
by: Oyekoya T. Ayonrinde
Published: (2021-06-01)

Ultrasound steatometry in patients with non-alcoholic fatty liver disease: pilot results
by: Darya Yu. Venidiktova, et al.
Published: (2019-04-01)