Design, Synthesis, and Neuroprotective Effects of a Series of Pyrazolines against 6-Hydroxydopamine-Induced Oxidative Stress

Design, Synthesis, and Neuroprotective Effects of a Series of Pyrazolines against 6-Hydroxydopamine-Induced Oxidative Stress

Parkinson’s disease (PD) is a chronic, progressive, and age-related neurodegenerative disorder characterized by the loss of midbrain dopaminergic neurons caused by the accumulation of free radicals and oxidative stress. Based on the neuroprotective properties of 2-pyrazoline derivatives, i...

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Bibliographic Details
Main Authors: Ahmet Özdemir, Belgin Sever, Mehlika Dilek Altıntop, Elif Kaya Tilki, Miriş Dikmen
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
Parkinson’s disease
neurodegeneration
2-pyrazoline
chalcone
6-hydroxydopamine
pharmacokinetic parameters
Online Access:http://www.mdpi.com/1420-3049/23/9/2151

Internet

http://www.mdpi.com/1420-3049/23/9/2151

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