Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer’s Mice

Alzheimer’s disease (AD) is a major public health concern worldwide. Advanced age and female sex are two of the most prominent risk factors for AD. AD is characterized by progressive neuronal loss, especially in the cortex and hippocampus, and mitochondrial dysfunction has been proposed to be an ear...

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Bibliographic Details
Main Authors: Jelena Djordjevic, Subir Roy Chowdhury, Wanda M. Snow, Claudia Perez, Chris Cadonic, Paul Fernyhough, Benedict C. Albensi
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/6/1541