Liraglutide Exerts Antidiabetic Effect via PTP1B and PI3K/Akt2 Signaling Pathway in Skeletal Muscle of KKAy Mice

Background. Liraglutide (a glucagon-like peptide 1 analog) was used for the treatment of type 2 diabetes (T2DM) which could produce glucose-dependent insulin secretion. Aim. The aim was to investigate whether liraglutide could improve myofibril and mitochondria injury in skeletal muscle and the mech...

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Bibliographic Details
Main Authors: Wenjun Ji, Xinlin Chen, Juan Lv, Meng Wang, Shuting Ren, Bingxiang Yuan, Bing Wang, Lina Chen
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/312452