Comparative Whole Genome Sequence Analysis and Biological Features of Clostridioides difficile Sequence Type 2‡

Comparative Whole Genome Sequence Analysis and Biological Features of Clostridioides difficile Sequence Type 2‡

Clostridioides difficile sequence type 2 (ST2) has been increasingly recognized as one of the major genotypes in China, while the genomic characteristics and biological phenotypes of Chinese ST2 strains remain to be determined. We used whole-genome sequencing and phylogenetic analysis to investigate...

Full description

Bibliographic Details
Main Authors:	Xingxing Xu, Qiao Bian, Yun Luo, Xiaojun Song, Shan Lin, Huan Chen, Qian Liang, Meixia Wang, Guangyong Ye, Bo Zhu, Liang Chen, Yi-Wei Tang, Xianjun Wang, Dazhi Jin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Series:	Frontiers in Microbiology
Subjects:	Clostridioides difficile whole genome sequencing ST2 tcdB genomic characteristics
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.651520/full

Similar Items

Ribotype Classification of Clostridioides difficile Isolates Is Not Predictive of the Amino Acid Sequence Diversity of the Toxin Virulence Factors TcdA and TcdB
by: Zhenghui Li, et al.
Published: (2020-06-01)

Loop mediated isothermal amplification of Clostridioides difficile isolates in gastrointestinal patients
by: Abbasi Montazeri, E., et al.
Published: (2022)

Quantitative Phosphoproteome Analysis of Clostridioides difficile Toxin B Treated Human Epithelial Cells
by: Johannes Junemann, et al.
Published: (2018-12-01)

High Serum Levels of Toxin A Correlate with Disease Severity in Patients with <i>Clostridioides difficile</i> Infection
by: Guido Granata, et al.
Published: (2021-09-01)

TcdB of Clostridioides difficile Mediates RAS-Dependent Necrosis in Epithelial Cells
by: Gerhard, R., et al.
Published: (2022)

TcdB of Clostridioides difficile Mediates RAS-Dependent Necrosis in Epithelial Cells
by: Gerhard, R., et al.
Published: (2022)

Systematic Evaluation of Parameters Important for Production of Native Toxin A and Toxin B from <i>Clostridioides difficile</i>
by: Aria Aminzadeh, et al.
Published: (2021-03-01)

Development of Neutralizing and Non-neutralizing Antibodies Targeting Known and Novel Epitopes of TcdB of Clostridioides difficile
by: Viola Fühner, et al.
Published: (2018-12-01)

Immunization with Recombinant TcdB-Encapsulated Nanocomplex Induces Protection against Clostridium difficile Challenge in a Mouse Model
by: Yi-Wen Liu, et al.
Published: (2017-07-01)

Prevalence, genotype and antimicrobial resistance of Clostridium difficile isolates from healthy pets in Eastern China
by: Yanxia Wei, et al.
Published: (2019-01-01)

The Role of Rho GTPases in Toxicity of Clostridium difficile Toxins
by: Shuyi Chen, et al.
Published: (2015-12-01)

The Enterotoxicity of Clostridium difficile Toxins
by: Hanping Feng, et al.
Published: (2010-07-01)

RstA Is a Major Regulator of Clostridioides difficile Toxin Production and Motility
by: Adrianne N. Edwards, et al.
Published: (2019-03-01)

A DNA vaccine targeting TcdA and TcdB induces protective immunity against Clostridium difficile
by: Bao-Zhong Zhang, et al.
Published: (2016-10-01)

Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection
by: Seung Woo Ahn, et al.
Published: (2021-09-01)

Microevolution within ST11 group Clostridioides difficile isolates through mobile genetic elements based on complete genome sequencing
by: Yuan Wu, et al.
Published: (2019-10-01)

Transition From PCR-Ribotyping to Whole Genome Sequencing Based Typing of Clostridioides difficile
by: Helena M. B. Seth-Smith, et al.
Published: (2021-06-01)

Gut Microbiota Composition Associated With Clostridium difficile-Positive Diarrhea and C. difficile Type in ICU Patients
by: Juping Duan, et al.
Published: (2020-05-01)

Major genetic discontinuity and novel toxigenic species in Clostridioides difficile taxonomy
by: Daniel R Knight, et al.
Published: (2021-06-01)

Clostridioides difficile Infection
Published: (2022)

Bacteriophage endolysins as a potential weapon to combat Clostridioides difficile infection
by: Shakhinur Islam Mondal, et al.
Published: (2020-11-01)

Occurrence of Clostridium difficile in two types of wastewater treatment plants
by: Mahnaz Nikaeen, et al.
Published: (2015-07-01)

Comparative genome and phenotypic analysis of three Clostridioides difficile strains isolated from a single patient provide insight into multiple infection of C. difficile
by: Uwe Groß, et al.
Published: (2018-01-01)

Risk factors for Clostridioides difficile infection and colonization among patients admitted to an intensive care unit in Shanghai, China
by: Yingchao Cui, et al.
Published: (2019-11-01)

Factors and Conditions That Impact Electroporation of Clostridioides difficile Strains
by: Disha Bhattacharjee, et al.
Published: (2020-03-01)

Bacteriophages Contribute to Shaping Clostridioides (Clostridium) difficile Species
by: Louis-Charles Fortier
Published: (2018-08-01)

Risks and Preventive Strategies for Clostridioides difficile Transmission to Household or Community Contacts during Transition in Healthcare Settings
by: Ramin Asgary, et al.
Published: (2021-07-01)

The microbial diversity following antibiotic treatment of Clostridioides difficile infection
by: Dana Binyamin, et al.
Published: (2021-04-01)

Human and Porcine Transmission of Clostridioides difficile Ribotype 078, Europe
by: Geraldine Moloney, et al.
Published: (2021-09-01)

National Surveillance for Clostridioides difficile Infection, Sweden, 2009–2016
by: Kristina Rizzardi, et al.
Published: (2018-09-01)

<i>Clostridioides difficile</i> as a Dynamic Vehicle for the Dissemination of Antimicrobial-Resistance Determinants: Review and In Silico Analysis
by: Philip Kartalidis, et al.
Published: (2021-06-01)

Investigational Treatment Agents for Recurrent Clostridioides difficile Infection (rCDI)
by: Kullar R, et al.
Published: (2020-10-01)

Burden of Clostridioides difficile infection (CDI) - a systematic review of the epidemiology of primary and recurrent CDI
by: Elaine Finn, et al.
Published: (2021-05-01)

Clostridioides difficile Toxin A-Induced Wnt/β-Catenin Pathway Inhibition Is Mediated by Rac1 Glucosylation
by: Conceição S. Martins, et al.
Published: (2020-08-01)

Costs Associated with the Treatment of Clostridioides Difficile Infections
by: Aleksandra Sierocka, et al.
Published: (2021-07-01)

Development and Implementation of Whole Genome Sequencing-Based Typing Schemes for Clostridioides difficile
by: Sandra Janezic, et al.
Published: (2019-10-01)

The molecular characters and antibiotic resistance of Clostridioides difficile from economic animals in China
by: Wen-Zhu Zhang, et al.
Published: (2020-03-01)

Microbiota in <i>Clostridioides difficile</i>-Associated Diarrhea: Comparison in Recurrent and Non-Recurrent Infections
by: Alessandra Gazzola, et al.
Published: (2020-09-01)

Usefulness of Fecal Calprotectin in the Management of Patients with Toxigenic <i>Clostridioides difficile</i>
by: Cecilia Suarez-Carantoña, et al.
Published: (2021-04-01)

Immune Profiling To Predict Outcome of Clostridioides difficile Infection
by: Mayuresh M. Abhyankar, et al.
Published: (2020-05-01)