A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 cases

<p class="p p-first" id="__p2">AIM: Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enteroco...

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Main Authors: O. Thompson, M. Rasmussen, A. Stefánsdóttir, B. Christensson, P. Åkesson
Format: Article
Language:English
Published: Copernicus Publications 2019-11-01
Series:Journal of Bone and Joint Infection
Online Access:https://jbji.copernicus.org/articles/4/285/2019/jbji-4-285-2019.pdf
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spelling doaj-5476e51edfea40a7a6d766187e845d5d2021-03-03T14:45:48ZengCopernicus PublicationsJournal of Bone and Joint Infection2206-35522019-11-01428529110.7150/jbji.35683A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 casesO. Thompson0M. Rasmussen1A. Stefánsdóttir2B. Christensson3P. Åkesson4Lund University, Department of Clinical Sciences Lund, Division of Infection Medicine and Skåne University Hospital, Department of Infectious Diseases, Lund, Sweden;Lund University, Department of Clinical Sciences Lund, Division of Infection Medicine and Skåne University Hospital, Department of Infectious Diseases, Lund, Sweden;Lund University, Department of Clinical Sciences Lund, Division of Orthopedics and Skåne University Hospital, Department of Orthopedics, Lund, Sweden.Lund University, Department of Clinical Sciences Lund, Division of Infection Medicine and Skåne University Hospital, Department of Infectious Diseases, Lund, Sweden;Lund University, Department of Clinical Sciences Lund, Division of Infection Medicine and Skåne University Hospital, Department of Infectious Diseases, Lund, Sweden;<p class="p p-first" id="__p2">AIM: Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enterococcal PJI, investigating treatment and outcome, as well as describing the affected patient population regarding demography and co-morbidities.</p><p id="__p3">METHODS: We identified all enterococcal PJIs in the Region of Skåne, Sweden, during a five-year period (2011-2015) and reviewed the patients' medical records.</p><p id="__p4">RESULTS: Fifty-five enterococcal PJIs were found. Enterococcus faecalis was the most frequently isolated species (84%), and poly-microbial infections were common (64%). Treatment with intention to cure was given to 43 (78%) cases. Debridement with retention of the implant and antibiotics (DAIR) was the most common surgical treatment strategy (71%), with a cure-rate of 72%. Overall cure-rate was 67%, and in cases where cure was intended, this was achieved in 80%.</p><p class="p p-last" id="__p5">CONCLUSIONS: When cure is aimed for, the prognosis for enterococcal PJI is not so poor, and DAIR treatment can provide adequate results in many cases.</p>https://jbji.copernicus.org/articles/4/285/2019/jbji-4-285-2019.pdf
collection DOAJ
language English
format Article
sources DOAJ
author O. Thompson
M. Rasmussen
A. Stefánsdóttir
B. Christensson
P. Åkesson
spellingShingle O. Thompson
M. Rasmussen
A. Stefánsdóttir
B. Christensson
P. Åkesson
A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 cases
Journal of Bone and Joint Infection
author_facet O. Thompson
M. Rasmussen
A. Stefánsdóttir
B. Christensson
P. Åkesson
author_sort O. Thompson
title A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 cases
title_short A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 cases
title_full A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 cases
title_fullStr A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 cases
title_full_unstemmed A population-based study on the treatment and outcome of enterococcal prosthetic joint infections. A consecutive series of 55 cases
title_sort population-based study on the treatment and outcome of enterococcal prosthetic joint infections. a consecutive series of 55 cases
publisher Copernicus Publications
series Journal of Bone and Joint Infection
issn 2206-3552
publishDate 2019-11-01
description <p class="p p-first" id="__p2">AIM: Enterococci cause 2-11% of all prosthetic joint infections (PJI) and are generally considered difficult to treat. However, study-results are not consistent. In this study we present a population-based case series of 55 cases with enterococcal PJI, investigating treatment and outcome, as well as describing the affected patient population regarding demography and co-morbidities.</p><p id="__p3">METHODS: We identified all enterococcal PJIs in the Region of Skåne, Sweden, during a five-year period (2011-2015) and reviewed the patients' medical records.</p><p id="__p4">RESULTS: Fifty-five enterococcal PJIs were found. Enterococcus faecalis was the most frequently isolated species (84%), and poly-microbial infections were common (64%). Treatment with intention to cure was given to 43 (78%) cases. Debridement with retention of the implant and antibiotics (DAIR) was the most common surgical treatment strategy (71%), with a cure-rate of 72%. Overall cure-rate was 67%, and in cases where cure was intended, this was achieved in 80%.</p><p class="p p-last" id="__p5">CONCLUSIONS: When cure is aimed for, the prognosis for enterococcal PJI is not so poor, and DAIR treatment can provide adequate results in many cases.</p>
url https://jbji.copernicus.org/articles/4/285/2019/jbji-4-285-2019.pdf
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