Characterization of nanoparticles combining polyamine detection with photodynamic therapy

Li et al develop PPAB-PyS nanoparticles that simultaneously allows intracellular imaging and ratiometric detection of the intracellular polyamine. With an additional potential to consume polyamines via an irreversible chemical reaction, the authors thus provide an alternative approach for photodynam...

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Main Authors: Wenting Li, Lingyun Wang, Tianlei Sun, Hao Tang, Brian Bui, Derong Cao, Ruibing Wang, Wei Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02317-5
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spelling doaj-5474ef861536426291baad744c91fe772021-07-04T11:13:53ZengNature Publishing GroupCommunications Biology2399-36422021-07-014111110.1038/s42003-021-02317-5Characterization of nanoparticles combining polyamine detection with photodynamic therapyWenting Li0Lingyun Wang1Tianlei Sun2Hao Tang3Brian Bui4Derong Cao5Ruibing Wang6Wei Chen7Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of TechnologyKey Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of TechnologyState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, TaipaState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, TaipaDepartment of Physics, University of Texas at ArlingtonKey Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of TechnologyState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, TaipaDepartment of Physics, University of Texas at ArlingtonLi et al develop PPAB-PyS nanoparticles that simultaneously allows intracellular imaging and ratiometric detection of the intracellular polyamine. With an additional potential to consume polyamines via an irreversible chemical reaction, the authors thus provide an alternative approach for photodynamic therapy with polyamine detection.https://doi.org/10.1038/s42003-021-02317-5
collection DOAJ
language English
format Article
sources DOAJ
author Wenting Li
Lingyun Wang
Tianlei Sun
Hao Tang
Brian Bui
Derong Cao
Ruibing Wang
Wei Chen
spellingShingle Wenting Li
Lingyun Wang
Tianlei Sun
Hao Tang
Brian Bui
Derong Cao
Ruibing Wang
Wei Chen
Characterization of nanoparticles combining polyamine detection with photodynamic therapy
Communications Biology
author_facet Wenting Li
Lingyun Wang
Tianlei Sun
Hao Tang
Brian Bui
Derong Cao
Ruibing Wang
Wei Chen
author_sort Wenting Li
title Characterization of nanoparticles combining polyamine detection with photodynamic therapy
title_short Characterization of nanoparticles combining polyamine detection with photodynamic therapy
title_full Characterization of nanoparticles combining polyamine detection with photodynamic therapy
title_fullStr Characterization of nanoparticles combining polyamine detection with photodynamic therapy
title_full_unstemmed Characterization of nanoparticles combining polyamine detection with photodynamic therapy
title_sort characterization of nanoparticles combining polyamine detection with photodynamic therapy
publisher Nature Publishing Group
series Communications Biology
issn 2399-3642
publishDate 2021-07-01
description Li et al develop PPAB-PyS nanoparticles that simultaneously allows intracellular imaging and ratiometric detection of the intracellular polyamine. With an additional potential to consume polyamines via an irreversible chemical reaction, the authors thus provide an alternative approach for photodynamic therapy with polyamine detection.
url https://doi.org/10.1038/s42003-021-02317-5
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