Characterization of nanoparticles combining polyamine detection with photodynamic therapy

Li et al develop PPAB-PyS nanoparticles that simultaneously allows intracellular imaging and ratiometric detection of the intracellular polyamine. With an additional potential to consume polyamines via an irreversible chemical reaction, the authors thus provide an alternative approach for photodynam...

Full description

Bibliographic Details
Main Authors: Wenting Li, Lingyun Wang, Tianlei Sun, Hao Tang, Brian Bui, Derong Cao, Ruibing Wang, Wei Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02317-5
Description
Summary:Li et al develop PPAB-PyS nanoparticles that simultaneously allows intracellular imaging and ratiometric detection of the intracellular polyamine. With an additional potential to consume polyamines via an irreversible chemical reaction, the authors thus provide an alternative approach for photodynamic therapy with polyamine detection.
ISSN:2399-3642