CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications

CD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, rheumatoid arthritis, and allergy to name only some...

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Main Authors: Drahomíra Holmannová, Martina Koláčková, Kateřina Kondělková, Pavel Kuneš, Jan Krejsek, Ctirad Andrýs
Format: Article
Language:English
Published: Karolinum Press 2012-01-01
Series:Acta Medica
Subjects:
Online Access:https://actamedica.lfhk.cuni.cz/55/2/0059/
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spelling doaj-5466d6d5ba47428695d8f90e4954f2c42020-11-24T22:24:03ZengKarolinum PressActa Medica1211-42861805-96942012-01-01552596510.14712/18059694.2015.56CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical ApplicationsDrahomíra Holmannová0Martina Koláčková1Kateřina Kondělková2Pavel Kuneš3Jan Krejsek4Ctirad Andrýs5Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Clinical Immunology and AllergologyCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, rheumatoid arthritis, and allergy to name only some. Many research projects are aimed to develop clinically valuable methods being based on the structure and function of these paired molecules. In this review, we would like to introduce CD200/CD200R functions in a clinical context.https://actamedica.lfhk.cuni.cz/55/2/0059/CD200CD200RInflammationImmunoregulationSelf-tolerance
collection DOAJ
language English
format Article
sources DOAJ
author Drahomíra Holmannová
Martina Koláčková
Kateřina Kondělková
Pavel Kuneš
Jan Krejsek
Ctirad Andrýs
spellingShingle Drahomíra Holmannová
Martina Koláčková
Kateřina Kondělková
Pavel Kuneš
Jan Krejsek
Ctirad Andrýs
CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications
Acta Medica
CD200
CD200R
Inflammation
Immunoregulation
Self-tolerance
author_facet Drahomíra Holmannová
Martina Koláčková
Kateřina Kondělková
Pavel Kuneš
Jan Krejsek
Ctirad Andrýs
author_sort Drahomíra Holmannová
title CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications
title_short CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications
title_full CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications
title_fullStr CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications
title_full_unstemmed CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications
title_sort cd200/cd200r paired potent inhibitory molecules regulating immune and inflammatory responses; part ii : cd 200/cd200r potential clinical applications
publisher Karolinum Press
series Acta Medica
issn 1211-4286
1805-9694
publishDate 2012-01-01
description CD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, rheumatoid arthritis, and allergy to name only some. Many research projects are aimed to develop clinically valuable methods being based on the structure and function of these paired molecules. In this review, we would like to introduce CD200/CD200R functions in a clinical context.
topic CD200
CD200R
Inflammation
Immunoregulation
Self-tolerance
url https://actamedica.lfhk.cuni.cz/55/2/0059/
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AT pavelkunes cd200cd200rpairedpotentinhibitorymoleculesregulatingimmuneandinflammatoryresponsespartiicd200cd200rpotentialclinicalapplications
AT jankrejsek cd200cd200rpairedpotentinhibitorymoleculesregulatingimmuneandinflammatoryresponsespartiicd200cd200rpotentialclinicalapplications
AT ctiradandrys cd200cd200rpairedpotentinhibitorymoleculesregulatingimmuneandinflammatoryresponsespartiicd200cd200rpotentialclinicalapplications
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