CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications
CD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, rheumatoid arthritis, and allergy to name only some...
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doaj-5466d6d5ba47428695d8f90e4954f2c42020-11-24T22:24:03ZengKarolinum PressActa Medica1211-42861805-96942012-01-01552596510.14712/18059694.2015.56CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical ApplicationsDrahomíra Holmannová0Martina Koláčková1Kateřina Kondělková2Pavel Kuneš3Jan Krejsek4Ctirad Andrýs5Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Clinical Immunology and AllergologyCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCharles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Cardiac SurgeryCD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, rheumatoid arthritis, and allergy to name only some. Many research projects are aimed to develop clinically valuable methods being based on the structure and function of these paired molecules. In this review, we would like to introduce CD200/CD200R functions in a clinical context.https://actamedica.lfhk.cuni.cz/55/2/0059/CD200CD200RInflammationImmunoregulationSelf-tolerance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Drahomíra Holmannová Martina Koláčková Kateřina Kondělková Pavel Kuneš Jan Krejsek Ctirad Andrýs |
spellingShingle |
Drahomíra Holmannová Martina Koláčková Kateřina Kondělková Pavel Kuneš Jan Krejsek Ctirad Andrýs CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications Acta Medica CD200 CD200R Inflammation Immunoregulation Self-tolerance |
author_facet |
Drahomíra Holmannová Martina Koláčková Kateřina Kondělková Pavel Kuneš Jan Krejsek Ctirad Andrýs |
author_sort |
Drahomíra Holmannová |
title |
CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications |
title_short |
CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications |
title_full |
CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications |
title_fullStr |
CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications |
title_full_unstemmed |
CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications |
title_sort |
cd200/cd200r paired potent inhibitory molecules regulating immune and inflammatory responses; part ii : cd 200/cd200r potential clinical applications |
publisher |
Karolinum Press |
series |
Acta Medica |
issn |
1211-4286 1805-9694 |
publishDate |
2012-01-01 |
description |
CD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, rheumatoid arthritis, and allergy to name only some. Many research projects are aimed to develop clinically valuable methods being based on the structure and function of these paired molecules. In this review, we would like to introduce CD200/CD200R functions in a clinical context. |
topic |
CD200 CD200R Inflammation Immunoregulation Self-tolerance |
url |
https://actamedica.lfhk.cuni.cz/55/2/0059/ |
work_keys_str_mv |
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