NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site.

To replicate, HIV-1 capitalizes on endogenous cellular activation pathways resulting in recruitment of key host transcription factors to its viral enhancer. RNA interference has been a powerful tool for blocking key checkpoints in HIV-1 entry into cells. Here we apply RNA interference to HIV-1 trans...

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Bibliographic Details
Main Authors: Shahin Ranjbar, Alla V Tsytsykova, Sang-Kyung Lee, Ricardo Rajsbaum, James V Falvo, Judy Lieberman, Premlata Shankar, Anne E Goldfeld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1698943?pdf=render