The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience

The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience

New developments in molecular neuropathology have evoked increased demands for postmortem human brain tissue. The New South Wales Tissue Resource Centre (TRC) at The University of Sydney has grown from a small tissue collection into one of the leading international brain banking facilities, which op...

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Main Authors: Antony Harding, Irina Dedova, Donna Sheedy, Nina Sundqvist, Therese Garrick, Clive G. Harper, Clare Hunt, Juliette Gillies
Format: Article
Language:English
Published: MDPI AG 2009-01-01
Series:International Journal of Molecular Sciences
Subjects:
Human
brain bank
schizophrenia
alcohol
postmortem
molecular neuropathology
genome
proteome
receptor binding
clinical characterization
Online Access:http://www.mdpi.com/1422-0067/10/1/366/
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spelling doaj-54621df9d5164246a7658fbfe84909452020-11-25T00:37:56ZengMDPI AGInternational Journal of Molecular Sciences1422-00672009-01-0110136638410.3390/ijms10010366The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre ExperienceAntony HardingIrina DedovaDonna SheedyNina SundqvistTherese GarrickClive G. HarperClare HuntJuliette GilliesNew developments in molecular neuropathology have evoked increased demands for postmortem human brain tissue. The New South Wales Tissue Resource Centre (TRC) at The University of Sydney has grown from a small tissue collection into one of the leading international brain banking facilities, which operates with best practice and quality control protocols. The focus of this tissue collection is on schizophrenia and allied disorders, alcohol use disorders and controls. This review highlights changes in TRC operational procedures dictated by modern neuroscience, and provides examples of applications of modern molecular techniques to study the neuropathogenesis of many different brain disorders.http://www.mdpi.com/1422-0067/10/1/366/Humanbrain bankschizophreniaalcoholpostmortemmolecular neuropathologygenomeproteomereceptor bindingclinical characterization
collection DOAJ
language English
format Article
sources DOAJ
author Antony Harding
Irina Dedova
Donna Sheedy
Nina Sundqvist
Therese Garrick
Clive G. Harper
Clare Hunt
Juliette Gillies
spellingShingle Antony Harding
Irina Dedova
Donna Sheedy
Nina Sundqvist
Therese Garrick
Clive G. Harper
Clare Hunt
Juliette Gillies
The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience
International Journal of Molecular Sciences
Human
brain bank
schizophrenia
alcohol
postmortem
molecular neuropathology
genome
proteome
receptor binding
clinical characterization
author_facet Antony Harding
Irina Dedova
Donna Sheedy
Nina Sundqvist
Therese Garrick
Clive G. Harper
Clare Hunt
Juliette Gillies
author_sort Antony Harding
title The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience
title_short The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience
title_full The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience
title_fullStr The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience
title_full_unstemmed The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience
title_sort importance of brain banks for molecular neuropathological research: the new south wales tissue resource centre experience
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1422-0067
publishDate 2009-01-01
description New developments in molecular neuropathology have evoked increased demands for postmortem human brain tissue. The New South Wales Tissue Resource Centre (TRC) at The University of Sydney has grown from a small tissue collection into one of the leading international brain banking facilities, which operates with best practice and quality control protocols. The focus of this tissue collection is on schizophrenia and allied disorders, alcohol use disorders and controls. This review highlights changes in TRC operational procedures dictated by modern neuroscience, and provides examples of applications of modern molecular techniques to study the neuropathogenesis of many different brain disorders.
topic Human
brain bank
schizophrenia
alcohol
postmortem
molecular neuropathology
genome
proteome
receptor binding
clinical characterization
url http://www.mdpi.com/1422-0067/10/1/366/
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