The expression of B7-H3 isoforms in newly diagnosed glioblastoma and recurrence and their functional role

The expression of B7-H3 isoforms in newly diagnosed glioblastoma and recurrence and their functional role

Abstract Short survival of glioblastoma (GBM) patients is due to systematic tumor recurrence. Our laboratory identified a GBM cell subpopulation able to leave the tumor mass (TM) and invade the subventricular zone (SVZ-GBM cells). SVZ-GBM cells escape treatment and appear to contribute to GBM recurr...

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Bibliographic Details
Main Authors: Marina Digregorio, Natacha Coppieters, Arnaud Lombard, Paul Noel Lumapat, Felix Scholtes, Bernard Rogister
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Acta Neuropathologica Communications
Subjects:
Glioblastoma
B7-H3
Isoforms
Recurrence
Online Access:https://doi.org/10.1186/s40478-021-01167-w

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