Oncostatin M Maintains Naïve Pluripotency of mESCs by Tetraploid Embryo Complementation (TEC) Assay

Oncostatin M Maintains Naïve Pluripotency of mESCs by Tetraploid Embryo Complementation (TEC) Assay

It has been well established that leukemia inhibitory factor (LIF) is essential for maintaining naïve pluripotency of embryonic stem cells (ESCs). Oncostatin M (OSM) is a member of the IL-6 family of cytokines which share gp130 as a receptor subunit, and the OSM-gp130 complex can recruit either LIF...

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Bibliographic Details
Main Authors: Xiaoying Ye, Chenglei Tian, Linlin Liu, Guofeng Feng, Kairang Jin, Haiying Wang, Jiyu Chen, Lin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
oncostatin M (OSM)
LIF
ESC
naïve pluripotency
TEC mice
telomere
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.675411/full

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