Allergy as an epithelial barrier disease

<p>Abstract</p> <p>The objective of this review is to focus on putative modified epithelial functions related to allergy. The dysregulation of the epithelial barrier might result in the allergen uptake, which could be the primary defect in the pathogenesis of allergic reaction. We...

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Main Authors:	Mattila Pirkko, Joenväärä Sakari, Renkonen Jutta, Toppila-Salmi Sanna, Renkonen Risto
Format:	Article
Language:	English
Published:	Wiley 2011-06-01
Series:	Clinical and Translational Allergy
Online Access:	http://www.ctajournal.com/content/1/1/5

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record_format	Article
spelling	doaj-5431d1bbaea5408286d08cb2da3680c52021-09-02T11:33:37ZengWileyClinical and Translational Allergy2045-70222011-06-0111510.1186/2045-7022-1-5Allergy as an epithelial barrier diseaseMattila PirkkoJoenväärä SakariRenkonen JuttaToppila-Salmi SannaRenkonen Risto<p>Abstract</p> <p>The objective of this review is to focus on putative modified epithelial functions related to allergy. The dysregulation of the epithelial barrier might result in the allergen uptake, which could be the primary defect in the pathogenesis of allergic reaction. We review the literature of the role of respiratory epithelium as an active barrier, how allergens are transported through it and how it senses the hostile environmental allergens and other dangerous stimuli.</p> http://www.ctajournal.com/content/1/1/5
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Mattila Pirkko Joenväärä Sakari Renkonen Jutta Toppila-Salmi Sanna Renkonen Risto
spellingShingle	Mattila Pirkko Joenväärä Sakari Renkonen Jutta Toppila-Salmi Sanna Renkonen Risto Allergy as an epithelial barrier disease Clinical and Translational Allergy
author_facet	Mattila Pirkko Joenväärä Sakari Renkonen Jutta Toppila-Salmi Sanna Renkonen Risto
author_sort	Mattila Pirkko
title	Allergy as an epithelial barrier disease
title_short	Allergy as an epithelial barrier disease
title_full	Allergy as an epithelial barrier disease
title_fullStr	Allergy as an epithelial barrier disease
title_full_unstemmed	Allergy as an epithelial barrier disease
title_sort	allergy as an epithelial barrier disease
publisher	Wiley
series	Clinical and Translational Allergy
issn	2045-7022
publishDate	2011-06-01
description	<p>Abstract</p> <p>The objective of this review is to focus on putative modified epithelial functions related to allergy. The dysregulation of the epithelial barrier might result in the allergen uptake, which could be the primary defect in the pathogenesis of allergic reaction. We review the literature of the role of respiratory epithelium as an active barrier, how allergens are transported through it and how it senses the hostile environmental allergens and other dangerous stimuli.</p>
url	http://www.ctajournal.com/content/1/1/5
work_keys_str_mv	AT mattilapirkko allergyasanepithelialbarrierdisease AT joenvaarasakari allergyasanepithelialbarrierdisease AT renkonenjutta allergyasanepithelialbarrierdisease AT toppilasalmisanna allergyasanepithelialbarrierdisease AT renkonenristo allergyasanepithelialbarrierdisease
_version_	1721175940078239744

Allergy as an epithelial barrier disease

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