Frizzled-7 as a Potential Therapeutic Target in Colorectal Cancer

Frizzled-7 as a Potential Therapeutic Target in Colorectal Cancer

We investigated whether one of the Wnt receptors, frizzled-7 (FZD7), functions in the canonical Wnt signaling pathway of colorectal cancer (CRC) cells harboring an APC or CTNNB1 mutation and may be a potential therapeutic target for sporadic CRCs. The expression level of FZD gene family members in...

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Bibliographic Details
Main Authors: Koji Ueno, Mikako Hiura, Yutaka Suehiro, Shoichi Hazama, Hiroshi Hirata, Masaaki Oka, Kohzoh Imai, Rajvir Dahiya, Yuji Hinoda
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800085

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http://www.sciencedirect.com/science/article/pii/S1476558608800085

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