Targeted siRNA Nanoparticles for Mammary Carcinoma Therapy

Targeted siRNA Nanoparticles for Mammary Carcinoma Therapy

Non-viral, polymeric-based, siRNA nanoparticles (NPs) have been proposed as promising gene delivery systems. Encapsulating siRNA in targeted NPs could confer improved biological stability, extended half-life, enhanced permeability, effective tumor accumulation, and therapy. In this work, a peptide d...

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Bibliographic Details
Main Authors: Meital Ben-David-Naim, Arie Dagan, Etty Grad, Gil Aizik, Mirjam M. Nordling-David, Alisa Morss Clyne, Zvi Granot, Gershon Golomb
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
nanoparticles
targeted delivery system
siRNA
osteopontin
mammary carcinoma
Online Access:https://www.mdpi.com/2072-6694/11/4/442

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