Effective Activation and Expansion of Canine Lymphocytes Using a Novel Nano-Sized Magnetic Beads Approach

Effective Activation and Expansion of Canine Lymphocytes Using a Novel Nano-Sized Magnetic Beads Approach

Expansion protocols for human T lymphocytes using magnetic beads, which serve as artificial antigen presenting cells (aAPCs), is well-studied. Yet, the efficacy of magnetic beads for propagation and functionality of peripheral blood lymphocytes (PBLs) isolated from companion dogs still remains limit...

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Bibliographic Details
Main Authors: Iwona Monika Szopa, Monika Granica, Joanna Katarzyna Bujak, Agata Łabędź, Maciej Błaszczyk, Chrystal Mary Paulos, Kinga Majchrzak-Kuligowska
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
adoptive cell transfer
canine T cells
cellular immunotherapy
domestic dog model
microbeads
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.604066/full

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