Inhibition of TNF-α Reverses the Pathological Resorption Pit Profile of Osteoclasts from Patients with Acute Charcot Osteoarthropathy

We hypothesised that tumour necrosis factor-α (TNF-α) may enhance receptor activator of nuclear factor-κβ ligand- (RANKL-) mediated osteoclastogenesis in acute Charcot osteoarthropathy. Peripheral blood monocytes were isolated from 10 acute Charcot patients, 8 diabetic patients, and 9 healthy contro...

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Bibliographic Details
Main Authors:	Nina L. Petrova, Peter K. Petrov, Michael E. Edmonds, Catherine M. Shanahan
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2015/917945

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