ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces

ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces

The bioactive substance producing strain, a marine bacterium A5S-46 was found in the antibacterial screening. This strain was isolated from the artificial sponge set in the coastal seawater at Iriomote islands (Japan). The crude extract from culture broth of the strain A5S-46 was assayed to the anti...

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Main Authors: Abdullah Rasyid, Kyoko Adachi
Format: Article
Language:English
Published: Universitas Gadjah Mada 2010-06-01
Series:Indonesian Journal of Chemistry
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/21683
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spelling doaj-541908417710490a96604ce80b0a01682020-11-24T22:01:15ZengUniversitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782010-06-017335035310.22146/ijc.2168314781ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED StreptomycesAbdullah Rasyid0Kyoko Adachi1Research Center for Oceanography, Indonesian Institute of Sciences Jl. Pasir Putih No. 1 Ancol Timur, Jakarta14430 IndonesiaMarine Biotechnology Institute,3-75-1 Heita, Kamaishi, Iwate 026-0001 JapanThe bioactive substance producing strain, a marine bacterium A5S-46 was found in the antibacterial screening. This strain was isolated from the artificial sponge set in the coastal seawater at Iriomote islands (Japan). The crude extract from culture broth of the strain A5S-46 was assayed to the antibacterial activity test against the seven kinds of bacterial test strains. The active substance accumulated in the both bacterial cells and culture supernatant. Based on the 1H NMR and the LC/PDA/MS data, the bioactive substance was identified to be actinomycin D.   Keywords: Marine bacteria, Actinomycin D, Antibacterial, Anticancerhttps://jurnal.ugm.ac.id/ijc/article/view/21683
collection DOAJ
language English
format Article
sources DOAJ
author Abdullah Rasyid
Kyoko Adachi
spellingShingle Abdullah Rasyid
Kyoko Adachi
ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces
Indonesian Journal of Chemistry
author_facet Abdullah Rasyid
Kyoko Adachi
author_sort Abdullah Rasyid
title ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces
title_short ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces
title_full ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces
title_fullStr ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces
title_full_unstemmed ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces
title_sort isolation of actinomycin d from marine derived streptomyces
publisher Universitas Gadjah Mada
series Indonesian Journal of Chemistry
issn 1411-9420
2460-1578
publishDate 2010-06-01
description The bioactive substance producing strain, a marine bacterium A5S-46 was found in the antibacterial screening. This strain was isolated from the artificial sponge set in the coastal seawater at Iriomote islands (Japan). The crude extract from culture broth of the strain A5S-46 was assayed to the antibacterial activity test against the seven kinds of bacterial test strains. The active substance accumulated in the both bacterial cells and culture supernatant. Based on the 1H NMR and the LC/PDA/MS data, the bioactive substance was identified to be actinomycin D.   Keywords: Marine bacteria, Actinomycin D, Antibacterial, Anticancer
url https://jurnal.ugm.ac.id/ijc/article/view/21683
work_keys_str_mv AT abdullahrasyid isolationofactinomycindfrommarinederivedstreptomyces
AT kyokoadachi isolationofactinomycindfrommarinederivedstreptomyces
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