Sensitive Detection of Measles Virus Infection in the Blood and Tissues of Humanized Mouse by One-step Quantitative RT-PCR

Live attenuated measles virus (MV) has long been recognized as a safe and effective vaccine, and it has served as the basis for development of various MV-based vaccines. However, because MV is a human-tropic virus, the evaluation of MV-based vaccines has been hampered by the lack of a small-animal m...

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Main Authors: Shota eIkeno, Moto-omi eSuzuki, Mahmod eMuhsen, Masayuki eIshige, Mie eKobayashi, Shinji eOhno, Makoto eTakeda, Tetsuo eNakayama, Yuko eMorikawa, Kazutaka eTerahara, Seiji eOkada, Haruko eTakeyama, Yasuko Tsunetsugu Yokota
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Microbiology
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Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00298/full