Systems analysis of human T helper17 cell differentiation uncovers distinct time-regulated transcriptional modules

Systems analysis of human T helper17 cell differentiation uncovers distinct time-regulated transcriptional modules

Summary: T helper (Th) 17 cells protect from infections and are pathogenic in autoimmunity. While human Th17 cell differentiation has been defined, the global and stepwise transcriptional changes accompanying this process remain uncharacterized. Herein, by performing transcriptome analysis of human...

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Bibliographic Details
Main Authors: Alessia Capone, Chiara Naro, Manuela Bianco, Marco De Bardi, Floriane Noël, Paolo Macchi, Luca Battistini, Vassili Soumelis, Elisabetta Volpe, Claudio Sette
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Systems Biology
Omics
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221004600

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