Association of COMT genotypes with S-COMT promoter methylation in growth-discordant monozygotic twins and healthy adults

<p>Abstract</p> <p>Background</p> <p>Catechol-O-Methyltransferase (COMT) plays a key role in dopamine and estrogen metabolism. Recently, COMT haplotypes rather than the single polymorphism Val158Met have been reported to underlie differences in protein expression by mod...

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Bibliographic Details
Main Authors: Schreiner Felix, El-Maarri Osman, Gohlke Bettina, Stutte Sonja, Nuesgen Nicole, Mattheisen Manuel, Fimmers Rolf, Bartmann Peter, Oldenburg Johannes, Woelfle Joachim
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/12/115