A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab

A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab

Research has indicated that serotonin (5-HT) modulates non-associative learning in a variety of invertebrate species. Recent work has demonstrated that the terrestrial hermit crab is a suitable animal model for non-associative learning phenomena, including habituation, sensitization, and dishabituat...

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Main Authors: Kirandeep Sumra, W. David Stahlman
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Saudi Journal of Biological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X18302250
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spelling doaj-53e1aed3ee2841f6abf293519ffb148b2020-11-25T02:21:20ZengElsevierSaudi Journal of Biological Sciences1319-562X2019-11-0126716211625A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crabKirandeep Sumra0W. David Stahlman1Department of Psychology, University of California, Los Angeles, USACorresponding author at: UMW Department of Psychological Science, 1301 College Ave., Fredericksburg, VA 22401, USA.; Department of Psychology, University of California, Los Angeles, USAResearch has indicated that serotonin (5-HT) modulates non-associative learning in a variety of invertebrate species. Recent work has demonstrated that the terrestrial hermit crab is a suitable animal model for non-associative learning phenomena, including habituation, sensitization, and dishabituation. We examined the potential role of a non-selective 5-HT antagonist, methysergide, in non-associative learning in the hermit crab. We administered methysergide prior to delivering repeated stimulus presentations of a looming visual predator. We found evidence for more rapid habituation relative to a control condition in which crabs did not receive the drug. These results indicate a role for 5-HT in the defensive behavior of the hermit crab and importantly, suggest a conserved role for 5-HT in modulating basic learning processes in invertebrates. Keywords: Serotonin, Methysergide, Sensitization, Hermit crab, Habituation, Risk assessmenthttp://www.sciencedirect.com/science/article/pii/S1319562X18302250
collection DOAJ
language English
format Article
sources DOAJ
author Kirandeep Sumra
W. David Stahlman
spellingShingle Kirandeep Sumra
W. David Stahlman
A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab
Saudi Journal of Biological Sciences
author_facet Kirandeep Sumra
W. David Stahlman
author_sort Kirandeep Sumra
title A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab
title_short A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab
title_full A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab
title_fullStr A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab
title_full_unstemmed A non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab
title_sort non-selective serotonin antagonist promotes rapid habituation in the terrestrial hermit crab
publisher Elsevier
series Saudi Journal of Biological Sciences
issn 1319-562X
publishDate 2019-11-01
description Research has indicated that serotonin (5-HT) modulates non-associative learning in a variety of invertebrate species. Recent work has demonstrated that the terrestrial hermit crab is a suitable animal model for non-associative learning phenomena, including habituation, sensitization, and dishabituation. We examined the potential role of a non-selective 5-HT antagonist, methysergide, in non-associative learning in the hermit crab. We administered methysergide prior to delivering repeated stimulus presentations of a looming visual predator. We found evidence for more rapid habituation relative to a control condition in which crabs did not receive the drug. These results indicate a role for 5-HT in the defensive behavior of the hermit crab and importantly, suggest a conserved role for 5-HT in modulating basic learning processes in invertebrates. Keywords: Serotonin, Methysergide, Sensitization, Hermit crab, Habituation, Risk assessment
url http://www.sciencedirect.com/science/article/pii/S1319562X18302250
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AT kirandeepsumra nonselectiveserotoninantagonistpromotesrapidhabituationintheterrestrialhermitcrab
AT wdavidstahlman nonselectiveserotoninantagonistpromotesrapidhabituationintheterrestrialhermitcrab
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