Total Synthesis of Gobiusxanthin Stereoisomers and Their Application to Determination of Absolute Configurations of Natural Products: Revision of Reported Absolute Configuration of Epigobiusxanthin

Total Synthesis of Gobiusxanthin Stereoisomers and Their Application to Determination of Absolute Configurations of Natural Products: Revision of Reported Absolute Configuration of Epigobiusxanthin

(3R)-Gobiusxanthin stereoisomers (1a–d) were synthesized by stereoselective Wittig reaction of the (3R)-C15-acetylenic tri-n-butylphosphonium salt 7 with C25-apocarotenal stereoisomers 5a,b and 14a,b bearing four kinds of 3,6-dihydroxy-ε-end groups. The validity of the reported stereochemistry of g...

Full description

Bibliographic Details
Main Authors: Yumiko Yamano, Kotaro Ematsu, Hiromasa Kurimoto, Takashi Maoka, Akimori Wada
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Marine Drugs
Subjects:
carotenoid
gobiusxanthin
epigobiusxanthin
total synthesis
chiral HPLC separation
absolute configuration
Online Access:http://www.mdpi.com/1660-3397/13/1/159

Similar Items

Similar Items