Synthetic Receptors Induce Anti Angiogenic and Stress Signaling on Human First Trimester Cytotrophoblast Cells

Synthetic Receptors Induce Anti Angiogenic and Stress Signaling on Human First Trimester Cytotrophoblast Cells

The cytotrophoblast (CTB) cells of the human placenta have membrane receptors that bind certain cardiotonic steroids (CTS) found in blood plasma. One of these, marinobufagenin, is a key factor in the etiology of preeclampsia. Herein, we used synthetic receptors (SR) to study their effectiveness on t...

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Bibliographic Details
Main Authors: Ahmed F. Pantho, Mason Price, AHM Zuberi Ashraf, Umaima Wajid, Maryam Emami Khansari, Afsana Jahan, Syeda H. Afroze, Md Mhahabubur Rhaman, Corey R. Johnson, Thomas J. Kuehl, Md. Alamgir Hossain, Mohammad Nasir Uddin
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:International Journal of Environmental Research and Public Health
Subjects:
angiogenic
cardiotonic steroids
cell signaling
cytotrophoblast
preeclampsia
synthetic receptors
Online Access:http://www.mdpi.com/1660-4601/14/5/517

Internet

http://www.mdpi.com/1660-4601/14/5/517

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