Validation of preimplantation genetic tests for aneuploidy (PGT-A) with DNA from spent culture media (SCM): concordance assessment and implication

Validation of preimplantation genetic tests for aneuploidy (PGT-A) with DNA from spent culture media (SCM): concordance assessment and implication

Abstract Background Spent culture medium (SCM) as a source of DNA for preimplantation genetic tests aneuploidy (PGT-A) has been widely discussed. Methods Seventy-five blastocysts that were donated for research provided a unique possibility in which multiple specimens, including trophectoderm (TE) bi...

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Bibliographic Details
Main Authors: Baoli Yin, Huijuan Zhang, Juanke Xie, Yubao Wei, Cuilian Zhang, Li Meng
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Reproductive Biology and Endocrinology
Subjects:
PGT
Aneuploidy
Chromosome concordance
Spent culture medium
Trophectoderm biopsy
NGS
Online Access:https://doi.org/10.1186/s12958-021-00714-3

Internet

https://doi.org/10.1186/s12958-021-00714-3

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