Adipose tissue area as a predictor for the efficacy of apatinib in platinum-resistant ovarian cancer: an exploratory imaging biomarker analysis of the AEROC trial

Adipose tissue area as a predictor for the efficacy of apatinib in platinum-resistant ovarian cancer: an exploratory imaging biomarker analysis of the AEROC trial

Abstract Background Vascular endothelial growth factor (VEGF)-targeted therapy is effective in patients with ovarian cancer. Whether adipose tissue (AT) could predict the efficacy of VEGF receptor (VEGFR) inhibitors in ovarian cancer is unknown. We aimed to evaluate the ability of distinct AT depots...

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Bibliographic Details
Main Authors: Xin Huang, Chuanbo Xie, Jie Tang, Wenzhuo He, Fan Yang, Wenfang Tian, Jundong Li, Qiuxia Yang, Jingxian Shen, Liangping Xia, Chunyan Lan
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Medicine
Subjects:
Ovarian cancer
Visceral adipose tissue
Subcutaneous adipose tissue
Intermuscular adipose tissue
Vascular endothelial growth factor receptor
Online Access:http://link.springer.com/article/10.1186/s12916-020-01733-4

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