P53 Mutations Change Phosphatidylinositol Acyl Chain Composition
Phosphatidylinositol phosphate (PIP) second messengers relay extracellular growth cues through the phosphorylation status of the inositol sugar, a signal transduction system that is deregulated in cancer. In stark contrast to PIP inositol head-group phosphorylation, changes in phosphatidylinositol (...
Main Authors: | Adam Naguib, Gyula Bencze, Dannielle D. Engle, Iok I.C. Chio, Tali Herzka, Kaitlin Watrud, Szilvia Bencze, David A. Tuveson, Darryl J. Pappin, Lloyd C. Trotman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-01-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714010213 |
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