ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation

ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation

Abstract Adenosine, its interacting A1 and A2A receptors, and particularly the variant rs5751876 in the A2A gene ADORA2A have been shown to modulate anxiety, arousal, and sleep. In a pilot positron emission tomography (PET) study in healthy male subjects, we suggested an effect of rs5751876 on in vi...

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Bibliographic Details
Main Authors: Christa Hohoff, Tina Kroll, Baoyuan Zhao, Nicole Kerkenberg, Ilona Lang, Kathrin Schwarte, David Elmenhorst, Eva-Maria Elmenhorst, Daniel Aeschbach, Weiqi Zhang, Bernhard T. Baune, Bernd Neumaier, Andreas Bauer, Jürgen Deckert
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-020-01085-w

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https://doi.org/10.1038/s41398-020-01085-w

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