Integrin αIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta

Integrin αIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta

Summary Integrins are transmembrane receptors that play important roles as modulators of cell behaviour through their adhesion properties and the initiation of signaling cascades. The αIIb integrin subunit (CD41) is one of the first cell surface markers indicative of hematopoietic commitment. αIIb p...

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Bibliographic Details
Main Authors: Jean-Charles Boisset, Thomas Clapes, Reinier Van Der Linden, Elaine Dzierzak, Catherine Robin
Format: Article
Language:English
Published: The Company of Biologists 2013-04-01
Series:Biology Open
Subjects:
Integrin
Hematopoietic stem cells
Aorta
Mouse development
Placenta
Fetal liver
CD41
Online Access:http://bio.biologists.org/content/2/5/525

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