"INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"

"INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"

Show other versions (1)

It has been shown in some investigations that cardiovascular events are the main causes of death in hemodialysis patients. The exact etiology is unknown but some of the articles have reported a relation between aluminium ions in the dialysis solution and cardiovascular disorders. To determine the pr...

Full description

Bibliographic Details
Main Authors: T. Mashhoodi, S. Zahedi-Asl AR. Sarkaki
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2004-10-01
Series:Acta Medica Iranica
Subjects:
Aluminium
phenylephrine
KCl
vasoconstriction
aorta
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/2756
id doaj-53a61d05196040f581a99c84c01b9ad0
record_format Article
spelling doaj-53a61d05196040f581a99c84c01b9ad02020-11-25T03:33:02ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942004-10-01425"INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA" T. Mashhoodi0 S. Zahedi-Asl AR. Sarkaki1 It has been shown in some investigations that cardiovascular events are the main causes of death in hemodialysis patients. The exact etiology is unknown but some of the articles have reported a relation between aluminium ions in the dialysis solution and cardiovascular disorders. To determine the probable effect of aluminium on vasculature function, in vitro effects of aluminium ion on vasoconstriction induced by KCl (30 mM) or phenylephrine (10 µM) were investigated using isolated rat aorta. AlCl3 (1-4 mM) decreased both KCl and phenylephrine induced contractions in a dose dependent manner (Phttps://acta.tums.ac.ir/index.php/acta/article/view/2756AluminiumphenylephrineKClvasoconstrictionaorta
collection DOAJ
language English
format Article
sources DOAJ
author T. Mashhoodi
S. Zahedi-Asl AR. Sarkaki
spellingShingle T. Mashhoodi
S. Zahedi-Asl AR. Sarkaki
"INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"
Acta Medica Iranica
Aluminium
phenylephrine
KCl
vasoconstriction
aorta
author_facet T. Mashhoodi
S. Zahedi-Asl AR. Sarkaki
author_sort T. Mashhoodi
title "INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"
title_short "INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"
title_full "INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"
title_fullStr "INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"
title_full_unstemmed "INHIBITORY EFFECT OF ALUMINIUM ON KCL AND PHENYLEPHRINE INDUCED CONTRACTION IN ISOLATED RAT AORTA"
title_sort "inhibitory effect of aluminium on kcl and phenylephrine induced contraction in isolated rat aorta"
publisher Tehran University of Medical Sciences
series Acta Medica Iranica
issn 0044-6025
1735-9694
publishDate 2004-10-01
description It has been shown in some investigations that cardiovascular events are the main causes of death in hemodialysis patients. The exact etiology is unknown but some of the articles have reported a relation between aluminium ions in the dialysis solution and cardiovascular disorders. To determine the probable effect of aluminium on vasculature function, in vitro effects of aluminium ion on vasoconstriction induced by KCl (30 mM) or phenylephrine (10 µM) were investigated using isolated rat aorta. AlCl3 (1-4 mM) decreased both KCl and phenylephrine induced contractions in a dose dependent manner (P
topic Aluminium
phenylephrine
KCl
vasoconstriction
aorta
url https://acta.tums.ac.ir/index.php/acta/article/view/2756
work_keys_str_mv AT tmashhoodi inhibitoryeffectofaluminiumonkclandphenylephrineinducedcontractioninisolatedrataorta
AT szahediaslarsarkaki inhibitoryeffectofaluminiumonkclandphenylephrineinducedcontractioninisolatedrataorta
_version_ 1724565141104623616

Similar Items