Acute respiratory distress caused by Neosartorya udagawae

• Main Authors: John J. Farrell, Douglas J. Kasper, Deepak Taneja, Sudhakar Baman, Lindsay M. O׳Rourke, Kristin S. Lowery, Rangarajan Sampath, Robert A. Bonomo, Stephen W. Peterson
• Format: Article
• Language: English
• Published: Elsevier 2014-10-01
• Series: Medical Mycology Case Reports
• Subjects: ARDS; Aspergillosis; Diagnostic mycology; Molecular microbiology
• Online Access: http://www.sciencedirect.com/science/article/pii/S221175391400030X
• ISSN: 2211-7539

We describe the first reported case of acute respiratory distress syndrome (ARDS) attributed to Neosartorya udagawae infection. This mold grew rapidly in cultures of multiple respiratory specimens from a previously healthy 43-year-old woman. Neosartorya spp. are a recently recognized cause of invasive disease in immunocompromised patients that can be mistaken for their sexual teleomorph, Aspergillus fumigatus. Because the cultures were sterile, phenotypic identification was not possible. DNA sequencing of ITS, calmodulin and β-tubulin genes supported identification of Neosartorya udagawae. Our case is the first report of ARDS associated with Neosartorya sp. infection and defines a new clinical entity.