Cytokinesis-block micronucleus assay of celecoxib and celecoxib derivatives

Celecoxib is used widely for the acute treatment of pain and for pain relief in various diseases. Furthermore, it shows potential in chemoprevention, although chronic treatment with celecoxib could lead to adverse effects like cardiovascular events. New derivatives of celecoxib were synthesised that...

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Bibliographic Details
Main Authors: Hauke Reimann, Quoc Anh Ngo, Helga Stopper, Henning Hintzsche
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750020304352