Dose-dependent effects of celecoxib on CB-1 agonist-induced antinociception in the mice

Dose-dependent effects of celecoxib on CB-1 agonist-induced antinociception in the mice

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Objective: Endocannabinoid produce analgesia that is comparable which of opioids. The mechanism of antinociceptive effects of (∆) - 9 tetrahydrocannabinol (THC) is suggested to be through cyclooxygenase (COX) pathway. In the present work, the effect of two extreme dose ranges of celecoxib (mg/kg and...

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Bibliographic Details
Main Authors:	Mohammad Reza Zarrindast, Soodeh Rezaee-Kalalj, Zahra Ghahremani, Mohammad Reza Jafari, Bijan Djahanguiri
Format:	Article
Language:	English
Published:	Tehran University of Medical Sciences 2009-06-01
Series:	Iranian Journal of Psychiatry
Online Access:	https://ijps.tums.ac.ir/index.php/ijps/article/view/509

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