Dose-dependent effects of celecoxib on CB-1 agonist-induced antinociception in the mice
Objective: Endocannabinoid produce analgesia that is comparable which of opioids. The mechanism of antinociceptive effects of (∆) - 9 tetrahydrocannabinol (THC) is suggested to be through cyclooxygenase (COX) pathway. In the present work, the effect of two extreme dose ranges of celecoxib (mg/kg and...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2009-06-01
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| Series: | Iranian Journal of Psychiatry |
| Online Access: | https://ijps.tums.ac.ir/index.php/ijps/article/view/509 |