Activity-dependent expression of Channelrhodopsin at neuronal synapses

Activity-dependent expression of Channelrhodopsin at neuronal synapses

Changes to subsets of dendritic spines are thought to be important for memory formation. Here, the authors develop a hybrid RNA/protein tool that allows for optogenetic stimulation of single synapses that have been tagged in an activity-dependent manner

Bibliographic Details
Main Authors: Francesco Gobbo, Laura Marchetti, Ajesh Jacob, Bruno Pinto, Noemi Binini, Federico Pecoraro Bisogni, Claudia Alia, Stefano Luin, Matteo Caleo, Tommaso Fellin, Laura Cancedda, Antonino Cattaneo
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01699-7
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spelling doaj-538e6614ad844188b60f0ec3906b6f082021-05-11T07:42:52ZengNature Publishing GroupNature Communications2041-17232017-11-018111410.1038/s41467-017-01699-7Activity-dependent expression of Channelrhodopsin at neuronal synapsesFrancesco Gobbo0Laura Marchetti1Ajesh Jacob2Bruno Pinto3Noemi Binini4Federico Pecoraro Bisogni5Claudia Alia6Stefano Luin7Matteo Caleo8Tommaso Fellin9Laura Cancedda10Antonino Cattaneo11Bio@SNS, Scuola Normale Superiore, piazza dei Cavalieri 7Bio@SNS, Scuola Normale Superiore, piazza dei Cavalieri 7Bio@SNS, Scuola Normale Superiore, piazza dei Cavalieri 7Bio@SNS, Scuola Normale Superiore, piazza dei Cavalieri 7Optical Approaches to Brain Function Laboratory, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, via Morego 30Optical Approaches to Brain Function Laboratory, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, via Morego 30Bio@SNS, Scuola Normale Superiore, piazza dei Cavalieri 7NEST, Scuola Normale Superiore, piazza San Silvestro 12Istituto di Neuroscienze, Consiglio Nazionale delle Ricerche, via Moruzzi 1Optical Approaches to Brain Function Laboratory, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, via Morego 30Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, via Morego 30Bio@SNS, Scuola Normale Superiore, piazza dei Cavalieri 7Changes to subsets of dendritic spines are thought to be important for memory formation. Here, the authors develop a hybrid RNA/protein tool that allows for optogenetic stimulation of single synapses that have been tagged in an activity-dependent mannerhttps://doi.org/10.1038/s41467-017-01699-7
collection DOAJ
language English
format Article
sources DOAJ
author Francesco Gobbo
Laura Marchetti
Ajesh Jacob
Bruno Pinto
Noemi Binini
Federico Pecoraro Bisogni
Claudia Alia
Stefano Luin
Matteo Caleo
Tommaso Fellin
Laura Cancedda
Antonino Cattaneo
spellingShingle Francesco Gobbo
Laura Marchetti
Ajesh Jacob
Bruno Pinto
Noemi Binini
Federico Pecoraro Bisogni
Claudia Alia
Stefano Luin
Matteo Caleo
Tommaso Fellin
Laura Cancedda
Antonino Cattaneo
Activity-dependent expression of Channelrhodopsin at neuronal synapses
Nature Communications
author_facet Francesco Gobbo
Laura Marchetti
Ajesh Jacob
Bruno Pinto
Noemi Binini
Federico Pecoraro Bisogni
Claudia Alia
Stefano Luin
Matteo Caleo
Tommaso Fellin
Laura Cancedda
Antonino Cattaneo
author_sort Francesco Gobbo
title Activity-dependent expression of Channelrhodopsin at neuronal synapses
title_short Activity-dependent expression of Channelrhodopsin at neuronal synapses
title_full Activity-dependent expression of Channelrhodopsin at neuronal synapses
title_fullStr Activity-dependent expression of Channelrhodopsin at neuronal synapses
title_full_unstemmed Activity-dependent expression of Channelrhodopsin at neuronal synapses
title_sort activity-dependent expression of channelrhodopsin at neuronal synapses
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-11-01
description Changes to subsets of dendritic spines are thought to be important for memory formation. Here, the authors develop a hybrid RNA/protein tool that allows for optogenetic stimulation of single synapses that have been tagged in an activity-dependent manner
url https://doi.org/10.1038/s41467-017-01699-7
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