Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway.

Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway.

Constitutive activation of the Rearranged during Transfection (RET) proto-oncogene leads to the development of MEN2A medullary thyroid cancer (MTC). The relatively clear genotype/phenotype relationship seen with RET mutations and the development of MEN2A is unusual in the fact that a single gene act...

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Bibliographic Details
Main Authors: Lyle J Burdine, Marie Schluterman Burdine, Linley Moreland, Brad Fogel, Lisa M Orr, Jennifer James, Richard H Turnage, Alan J Tackett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4466258?pdf=render

Internet

http://europepmc.org/articles/PMC4466258?pdf=render

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