Teratogenic effect of formaldehyde in rabbits

Thirty three pregnant rabbits were exposed to vapour of 10% formaldehyde (12 ppm) throughout the gestation period to know its effect on newborns. The results showed no abortion or foetal mortality but there were some anomalies (23.8%) among the newborns rabbits which includes: meromelia (6.8%), ence...

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Bibliographic Details
Main Author: A. A. Al–Saraj
Format: Article
Language:Arabic
Published: University of Mosul, College of Veterinary Medicine 2009-01-01
Series:Iraqi Journal of Veterinary Sciences
Subjects:
Online Access:http://www.vetmedmosul.org/ijvs/2009no1e2.htm
Description
Summary:Thirty three pregnant rabbits were exposed to vapour of 10% formaldehyde (12 ppm) throughout the gestation period to know its effect on newborns. The results showed no abortion or foetal mortality but there were some anomalies (23.8%) among the newborns rabbits which includes: meromelia (6.8%), encephalocele (6.1%), Oligodactyly (4.1%), Umbilical hernia (3.4%) and Short tail (3.4%); besides that small for date and decrease in the body weight of the newborns were also noticed. These findings suggest that formaldehyde is a teratogenic agent.
ISSN:1607-3894
2071-1255