Tumor mutation burden estimated by a 69-gene-panel is associated with overall survival in patients with diffuse large B-cell lymphoma

Tumor mutation burden estimated by a 69-gene-panel is associated with overall survival in patients with diffuse large B-cell lymphoma

Abstract Background Tumor mutation burden (TMB) as estimated by cancer gene panels (CGPs) has been confirmed to be associated with prognosis and is effective in predicting clinical benefit from immune checkpoint blockade (ICB) in solid tumors. However, whether the TMB calculated by CGPs is associate...

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Bibliographic Details
Main Authors: Cunte Chen, Sichu Liu, Xinmiao Jiang, Ling Huang, Feili Chen, Xiaojun Wei, Hanguo Guo, Yang Shao, Yangqiu Li, Wenyu Li
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Experimental Hematology & Oncology
Subjects:
TMB
Gene panel
Prognosis
Biomarker
Diffuse large B-cell lymphoma
Online Access:https://doi.org/10.1186/s40164-021-00215-4

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