Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia
Abstract Changes in cell metabolism and metabolic adaptation are hallmark features of many cancers, including leukemia, that support biological processes involved into tumor initiation, growth, and response to therapeutics. The discovery of mutations in key metabolic enzymes has highlighted the impo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-07-01
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| Series: | BMC Biology |
| Online Access: | http://link.springer.com/article/10.1186/s12915-019-0670-4 |