Synchrotron X-ray induced acoustic imaging

Abstract X-ray induced acoustic imaging (XAI) is an emerging biomedical imaging technique that can visualize X-ray absorption contrast at ultrasound resolution with less ionizing radiation exposure than conventional X-ray computed tomography. So far, medical linear accelerators or industrial portabl...

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Main Authors: Seongwook Choi, Eun-Yeong Park, Sinyoung Park, Jong Hyun Kim, Chulhong Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83604-3
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spelling doaj-53364a7f11174add9950d3e4f580ff3d2021-02-21T12:36:14ZengNature Publishing GroupScientific Reports2045-23222021-02-011111710.1038/s41598-021-83604-3Synchrotron X-ray induced acoustic imagingSeongwook Choi0Eun-Yeong Park1Sinyoung Park2Jong Hyun Kim3Chulhong Kim4Department of Electrical Engineering and Creative IT Engineering, Medical Device Innovation Center, Pohang University of Science and TechnologyDepartment of Electrical Engineering and Creative IT Engineering, Medical Device Innovation Center, Pohang University of Science and TechnologyDepartment of Electrical Engineering and Creative IT Engineering, Medical Device Innovation Center, Pohang University of Science and TechnologyDepartment of Mechanical Engineering, Pohang University of Science and TechnologyDepartment of Electrical Engineering and Creative IT Engineering, Medical Device Innovation Center, Pohang University of Science and TechnologyAbstract X-ray induced acoustic imaging (XAI) is an emerging biomedical imaging technique that can visualize X-ray absorption contrast at ultrasound resolution with less ionizing radiation exposure than conventional X-ray computed tomography. So far, medical linear accelerators or industrial portable X-ray tubes have been explored as X-ray excitation sources for XAI. Here, we demonstrate the first feasible synchrotron XAI (sXAI). The synchrotron generates X-rays, with a dominant energy of 4 to 30 keV, a pulse-width of 30 ps, a pulse-repetition period of 2 ns, and a bunch-repetition period of 940 ns. The X-ray induced acoustic (XA) signals are processed in the Fourier domain by matching the signal frequency with the bunch-repetition frequency. We successfully obtained two-dimensional XA images of various lead targets. This novel sXAI tool could complement conventional synchrotron applications.https://doi.org/10.1038/s41598-021-83604-3
collection DOAJ
language English
format Article
sources DOAJ
author Seongwook Choi
Eun-Yeong Park
Sinyoung Park
Jong Hyun Kim
Chulhong Kim
spellingShingle Seongwook Choi
Eun-Yeong Park
Sinyoung Park
Jong Hyun Kim
Chulhong Kim
Synchrotron X-ray induced acoustic imaging
Scientific Reports
author_facet Seongwook Choi
Eun-Yeong Park
Sinyoung Park
Jong Hyun Kim
Chulhong Kim
author_sort Seongwook Choi
title Synchrotron X-ray induced acoustic imaging
title_short Synchrotron X-ray induced acoustic imaging
title_full Synchrotron X-ray induced acoustic imaging
title_fullStr Synchrotron X-ray induced acoustic imaging
title_full_unstemmed Synchrotron X-ray induced acoustic imaging
title_sort synchrotron x-ray induced acoustic imaging
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-02-01
description Abstract X-ray induced acoustic imaging (XAI) is an emerging biomedical imaging technique that can visualize X-ray absorption contrast at ultrasound resolution with less ionizing radiation exposure than conventional X-ray computed tomography. So far, medical linear accelerators or industrial portable X-ray tubes have been explored as X-ray excitation sources for XAI. Here, we demonstrate the first feasible synchrotron XAI (sXAI). The synchrotron generates X-rays, with a dominant energy of 4 to 30 keV, a pulse-width of 30 ps, a pulse-repetition period of 2 ns, and a bunch-repetition period of 940 ns. The X-ray induced acoustic (XA) signals are processed in the Fourier domain by matching the signal frequency with the bunch-repetition frequency. We successfully obtained two-dimensional XA images of various lead targets. This novel sXAI tool could complement conventional synchrotron applications.
url https://doi.org/10.1038/s41598-021-83604-3
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AT eunyeongpark synchrotronxrayinducedacousticimaging
AT sinyoungpark synchrotronxrayinducedacousticimaging
AT jonghyunkim synchrotronxrayinducedacousticimaging
AT chulhongkim synchrotronxrayinducedacousticimaging
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