New avenue in the treatment of temporal lobe epilepsy by classical anti-epileptics: A hypothetical establishment of executioner Caspase 3 inactivation by molecular modeling

New avenue in the treatment of temporal lobe epilepsy by classical anti-epileptics: A hypothetical establishment of executioner Caspase 3 inactivation by molecular modeling

Patients with temporal lobe epilepsy (TLE) are prescribed first-line antiepileptic drugs and surgery to the management of this disorder. Unfortunately, the surgical treatment has been shown to be beneficial for the selected patients but fails to provide a seizure-free outcome in 20-30% of TLE patien...

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Bibliographic Details
Main Authors: M Vijey Aanandhi, Debojit Bhattacherjee, Anirban Ray, P Samuel Gideon George
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Caspase 3
Fas-associated death domain
Procaspase 8
quantitative structure toxicity relationship
temporal lobe epilepsy
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2015;volume=6;issue=2;spage=65;epage=74;aulast=Aanandhi

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