A Case of Burkitt's Lymphoma in a Child Presenting with Obstructive Jaundice and Requiring Surgical Intervention
Burkitt's lymphoma is a high-grade B non-Hodgkin lymphoma (NHL) and rarely presents with jaundice. We discuss the case of a 6-year-old male child presenting with fever, jaundice, and abdominal distention. Computed tomographic (CT) scan of the abdomen revealed a heterogeneous lymph node mass at...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical Publishers, Inc.
2018-07-01
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| Series: | Asian Journal of Oncology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676764 |
| Summary: | Burkitt's lymphoma is a high-grade B non-Hodgkin lymphoma (NHL) and rarely presents with jaundice. We discuss the case of a 6-year-old male child presenting with fever, jaundice, and abdominal distention. Computed tomographic (CT) scan of the abdomen revealed a heterogeneous lymph node mass at the pancreatic head with intrahepatic biliary dilation. Serum bilirubin was 26 mg/dL with direct fraction of 12.4 mg/dL. Biopsy and staging confirmed the diagnosis of Burkitt's lymphoma stage 3, group B. In view of hyperbilirubinemia, chemotherapeutic drugs doses were modified and rituximab was added. Persistent jaundice necessitated percutaneous biliary drainage so that chemotherapy could be continued. Despite complete response, jaundice and biliary dilatation remained. Hence, a side-to-side choledochoduodenostomy was performed after which the liver function normalized. Presently the child is well. NHL is a chemosensitive disease. If the serum bilirubin does not normalize quickly, biliary drainage is essential to allow administration of curative chemotherapy and prevent chronic liver damage. |
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| ISSN: | 2454-6798 2455-4618 |