The effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mice myocardial morphology

The effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mice myocardial morphology

ABSTRACT: Studies have demonstrated sympathetic cardiac denervation in the MPTP mouse model. MPTP toxicity causes sympathetic nerve damage and depletion of heart norepinephrine. Previous evaluations of impairments in heart innervation have been based on imaging, electrophysiological and biochemical...

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Bibliographic Details
Main Authors:	Tais H.C. Sasahara, Marcia R.F. Machado
Format:	Article
Language:	English
Published:	Colégio Brasileiro de Patologia Animal (CBPA)
Series:	Pesquisa Veterinária Brasileira
Subjects:	Methyl phenyl tetrahydropyridine MPTP mice myocardial morphology heart rodent stereology
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2019000500364&lng=en&tlng=en

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