Advanced gestational trophoblastic disease: A case report of medical management prior to surgical intervention

• Main Authors: Ann Lehto, Kyle Hitscherich, Olga Argeros
• Format: Article
• Language: English
• Published: Elsevier 2018-07-01
• Series: Case Reports in Women's Health
• Online Access: http://www.sciencedirect.com/science/article/pii/S2214911218300614

Background: Gestational trophoblastic disease (GTD) is a rare developmental form of proliferative trophoblastic tissue. Sparse literature exists regarding the optimal management of patients with advanced GTD, but the definitive treatment is urgent surgical intervention. Case: A 48-year-old woman presented advanced GTD. She was medically managed for hypertension and hyperthyroidism prior to surgical intervention in order to minimize the risk of anesthetic and surgical complications. Conclusion: Advanced GTD is rare. Undetected GTD can result in complications such as thyrotoxicosis, which poses substantial risks in the peri-operative period. Appropriate identification and management of this clinical problem are essential to prevent complications as well as subsequent malignant sequelae. Keywords: Molar pregnancy, Hydatidiform mole, Thyrotoxicosis, Medical optimization