14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr

14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr

<p>Abstract</p> <p>Background</p> <p>Despite continuing advances in our understanding of AIDS pathogenesis, the mechanism of CD4+ T cell depletion in HIV-1-infected individuals remains unclear. The HIV-1 Vpr accessory protein causes cell death, likely through a mechanis...

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Bibliographic Details
Main Authors: Sakai Keiko, Barnitz Robert A, Bolton Diane L, Lenardo Michael J
Format: Article
Language:English
Published: BMC 2008-04-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/3/1/17

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